NL-OMON20502
Recruiting
Not Applicable
eurotoxic changes in cerebral glucose metabolism during anaesthesia and major surgery; is the polyol pathway activated?
Sponsor: Amsterdam UMC. location AMC, Department of Anesthesiology0 sites16 target enrollmentTBD
Conditionscerebral glucose metabolismpolyol pathwayPostoperative cognitive dysfunction (POCD)hyperglycemiadeliriumneurocognitiveCerebrospinal fluid (CSF)sorbitolfructosethoracic aortic surgeryMontreal Cognitive Assessment (MoCA)Liquor cerebrospinalishersenvochtpolyol routecerebraal glucose metabolismehyperglykemiedelierpostoperatieve cognitieve dysfunctie (POCD)thoracale aorta chirurgie
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- cerebral glucose metabolism
- Sponsor
- Sponsor: Amsterdam UMC. location AMC, Department of Anesthesiology
- Enrollment
- 16
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients undergoing elective thoracic aortic surgery without pre\-existing brain disease and without diabetes mellitus who are able and willing to participate in the study and can provide written informed consent. Patients must be 18 years or older.
Exclusion Criteria
- •Patients undergoing elective thoracic aortic surgery with pre\-existing brain disease and/or diabetes mellitus. Patients who are unable to understand or fill\-in questionnaires in Dutch will also be excluded from the study.
Outcomes
Primary Outcomes
Not specified
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