Weefselonderzoek van het baarmoederslijmvlies
Recruiting
- Conditions
- Endometrial cancer, endometrial hyperplasia and endometrial intraepithelial Neoplasia (EIN)
- Registration Number
- NL-OMON26300
- Lead Sponsor
- Erasmus MC
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 500
Inclusion Criteria
Patients, aged 40 years and older, visiting the outpatient clinic with any indication for endometrial biopsy following the Dutch guidelines and common practice. At the distinction of the gynaecologist samples are either obtained by an office sampling device, or by hysteroscopy.
Exclusion Criteria
Age < 40
Not able to give informed consent
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method -What is the accuracy of the EIN diagnosed in an office setting (sampling devices and hysteroscopic biopsies)?
- Secondary Outcome Measures
Name Time Method -What is the risk of a malignancy after EIN in samples obtained in an office setting (office endometrial sampling as well as hysteroscopy)?<br>-Do samples obtained in an office setting (office endometrial sampling as well as hysteroscopy) contains sufficient material to diagnose EIN?<br>-How do EIN and hyperplasia correlate in samples obtained in an office setting (office endometrial sampling as well as hysteroscopy)?<br>- Do gynaecologist adhere to the current Dutch guideline postmenopausal bleeding (11.2015)<br>