NL-OMON38470
已完成
不适用
In vivo REsponse evaluation of colorectal liver metastases during systemic therapy using optical SPECTroscopy techniques: a pilot study - RESPECT study
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- colorectal livermetastases
- 发起方
- Philips Research
- 入组人数
- 22
- 状态
- 已完成
- 最后更新
- 去年
概览
简要总结
暂无简介。
研究者
入排标准
入选标准
- •\- Non\-resectable colorectal liver metastases
- •\- Liver metastases of which a histological biopsy can safely be obtained:
- •\* Patients with safely accessible liver lesions according to an intervention\-radiologist.
- •\* Patients not known with bleeding disorders (such as hemophilia) or bleeding complications from biopsies, dental procedures or surgery.
- •\* Patients not using any anti\-coagulant medication at the time of biopsy: all aspirin derivatives, NSAID\*s, coumarines, platelet function inhibitors, heparins (including LMWHs) and oral factor Xa inhibitors are not allowed, unless medication can either be safely stopped or counteracted.
- •\* Adequate hematology and coagulation status as measured by:
- •\* Hb \> 6\.0 mmol/L
- •\* Platelet count \> 100 x 109/L
- •\* PT \< 1\.5 x Upper limit of normal (ULN)
- •\* APTT \< 1\.5 x ULN
排除标准
- •\- Patients with suspected sensitivity to light; e.g. patients who have had photodynamic therapy
- •\-Patients who have higher risk of bleeding, such as patients with coagulopathy or patients who receive anticoagulants
结局指标
主要结局
未指定
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