use of muscle flap in reducing leak rate after radiation therapy and surgery for larynx cancer
- Conditions
- Health Condition 1: null- Patients suffering from laryngeal cancer
- Registration Number
- CTRI/2018/05/014337
- Lead Sponsor
- Tata memorial hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
1-Recurrent / residual lesions irrespective of histology of larynx and hypopharynx previously
treated with radiotherapy/ chemoradiotherapy undergoing salvage total laryngectomy.
2-Patients in whom primary pharyngeal closure is possible with no need for pharyngeal
reconstruction to augment pharyngeal mucosa closure.
3- Patients with age between 18 years -70 years
4- Patients with dysfunctional larynx as deemed by the tumor board decision with negative
histopathology report. Dysfunctional larynx may include: persistent tracheostomy,
chondronecrosis, persistent nasogastric tube use, and aspiration
1-Treatment naive patient with no prior radiotherapy/chemo-radiotherapy.
2-Patients suitable for conservation laryngeal surgery.
3-Patients requiring pharyngeal reconstruction for pharyngeal mucosa closure in whom
primary pharyngeal closure not possible.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method