Ventilation's Parameters Applied in Emergency Medicine. A Prospective Observational Study

Completed

• Conditions: Mechanical Ventilation; Protective Ventilation; Acute Respiratory Distress Syndrome; Survival

• Registration Number: NCT03351920
• Lead Sponsor: Poitiers University Hospital

Brief Summary

To prospectively assess the mechanical ventilation management when its provided by Emergency Physicians in French Hospital, and to assess complications and outcome of these patients.

The study could be measure the proportion of patients developing an Acute Respiratory Failure Distress after a take care of by French Emergency Departments.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-10-24
• Study Start: 2017-11-07
• Study First Submitted QC: 2017-11-21
• Study First Posted: 2017-11-24
• Primary Completion: 2019-07-22
• Study Completion: 2019-08-08
• Status Verified: 2020-02
• Last Update Submitted: 2020-02-06
• Last Update Posted: 2020-02-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 229

Inclusion Criteria

• Age equal or over 18 years old
• Needing a invasive or noninvasive mechanical ventilation
• Mechanical ventilation initiated in Prehospital or IntraHospital Emergency Department by an Emergency Physician

Exclusion Criteria

• Age under 18 years old

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Proportion of patients benefiting of a early low-volume ventilation initiated Emergency Department or Prehospital Care.	Day 1	Early Low volume ventilation will be defined according to a VtE \< 8mL/lg

Secondary Outcome Measures

Name	Time	Method
Proportion of patients benefiting of an early protective ventilation in Emergency Departments	Day 1
Proportion of survival from day 1 to Day 8, and to day 28	from Day 1 to Day 8 and Day 28
Indication to mechanical ventilation in Prehospital care and Emergency Departments	Day 1
Mechanical Ventilation Duration in Emergency Departments	Day 1
Mechanical ventilation settings in Emergency Departments	Day 1	Recorded settings will be Ventilation mode, Tidal volume or Pressure Support Positive End Expiratory Pressure, Ventilation Rate, I : E ratio or Inspiratory Flow or Inspiratory Time.
Proportion of patients with acute respiratory distress syndrome according to the Berlin Definition during the first eight days of following.	from Day 1 to Day 8 and Day 28	ARDS will be defined according to the Berlin definition.

Trial Locations

Locations (7)

Pierre-Marie Noël; 🇫🇷 Brest, France

Pierre-Arnaud Fort; 🇫🇷 Agen, France

CHU de Bordeaux; 🇫🇷 Bordeaux, France

Marjanovic Nicolas; 🇫🇷 Poitiers, France

Thomas Lenormand; 🇫🇷 Lorient, France

CH de Niort; 🇫🇷 Niort, France

Paul Fievet; 🇫🇷 La Rochelle, France