The Lipid Profile of the Skin Surface in Acne
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Skin lipid profile of acne and healthy patients
研究概览
简要总结
The purpose of this study is to evaluate the differences in the skin lipid profile of patients with and without acne. Secondly, the goal is to learn more about what the effects of retinoinds (topical and systemic) are on the the skin lipid profile. We hypothesize that the skin lipid profile of subjects with acne will be lower in inflammatory lipids in comparison to subjects without acne.
详细描述
Skin lipid profile will be conducted via sebutapes- adhesive tapes that painlessly absorbs sebum from the face. These tapes will be placed on the face for 1 hour. A photograph of the face will be taken during each study visit. A sebumeter will also be used to measure skin sebum secretion rate.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 12 Years 至 30 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age 12 to 30 years
- •have been prescribed tretinoin OR isotretinoin
排除标准
- •those who have taken isotretinoin (systemic)
- •those who used tretinoin or other topical retinoid within two weeks of starting the study
- •those with seborrheic dermatitis, rosacea, or polycystic ovary syndrome
- •those who are pregnant, prisoners, or cognitively impaired
- •those who do not fit the inclusion criteria
研究组 & 干预措施
Acne Group, Topical Retinoid
These subjects have been prescribed a topical retinoid for their acne. They will participate in the study for a period of 1 month.
干预措施: Tretinoin or Adapalene (Drug)
Acne Group, Isotretinoin
These subjects have been prescribed isotretinoin for their acne. They will participate in the study for a period of 5-6 months.
干预措施: Isotretinoin (Drug)
结局指标
主要结局
Skin lipid profile of acne and healthy patients
时间窗: baseline visit
Compare the skin lipid profile of acne and healthy patients at baseline
次要结局
- Skin lipid profile of acne patients after treatment(at 1 month and 4-5 months of treatment)