Technology in Motion (TIM): Unobtrusive assessment of motor (dys)functio

Completed

• Conditions: cerebrovascular accident (CVA; stroke); Parkinson's Disease (PD); tremor; 10028037

• Registration Number: NL-OMON43825
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Trial ended prematurely

Detailed Description

Not available

Study Timeline

• Study Completion: 2018-05-01
• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 190

Inclusion Criteria

General: 18 years or older, male/female, have command of the Dutch language.
Additional for stroke: survivor of a cerebrovascular accident (stroke)
Additional for PD: Diagnosed with PD according to the UK PD Brain Bank criteria
Additional for patients with tremor: tremor of the hand and/or arm, having a scheduled visit for tremor assessment at the Clinical Neurophysiology outpatient clinic at LUMC.
Additional for healthy controls: normal function of both arms, normal gait and balance function, normal cognitive function (MoCA score > 26), normal or corrected to normal vision

Exclusion Criteria

General:
* additional neurological diseases and/or orthopedic problems interfering with hand/arm function or balance/gait function
* unable to comply with the protocol, i.e. insufficient general fitness or cognitive/communicative inability to understand instructions and participate in the measurement
* inability to walk with help of one person (for the *gait and balance* experiment only);Additional for stroke:
* <12 weeks after stroke
* established Hereditary Cerebral Hemorrhage With Amyloidosis - Dutch type (HCHWA-D)
* absence of any voluntary control of the paretic arm (for the *reaching and grasping* experiment only)

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Kinematic parameters obtained for reaching and grasping (e.g., maximum active<br /><br>range of motion, accuracy, velocity and smoothness of reach and grasp<br /><br>movements), for gait and balance (e.g., step length, step time, gait asymmetry,<br /><br>performance on an obstacle avoidance task), and for tremor (frequency,<br /><br>amplitude) as a function of task- and environmental conditions. </p><br>