ISRCTN95151471已完成未知
Antidyskinetic properties of topiramate: a double-blind, placebo-controlled trial in patients with Parkinson's disease and levodopa-induced dyskinesias
Salford Royal NHS Foundation Trust (UK)0 个研究点目标入组 30 人开始时间: 2008年7月2日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Both males and females, no age limits
- •2. Patients with Parkinson's disease as defined by UK Parkinson's Disease Society Brain Bank criteria
- •3. Current use of levodopa, dose to be stable for one month prior to enrolment
- •4. Stable levodopa-induced dyskinesias
排除标准
- •1. Hypersensitivity to topiramate or its excipients
- •2. Prior surgery for PD
- •3. Hoehn and Yahr score of 5 when off
- •4. Dementia
- •5. History of nephrolithiasis, renal impairment, liver disease, glaucoma
- •6. Pregnancy and breastfeeding
- •7. Premenopausal females and males not using adequate contraception
- •8. Use of other antiepileptic drugs, carbonic anhydrase inhibitors, metformin, digoxin or illicit drugs
研究者
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Antidyskinetic Properties of Topiramate: A Double-Blind, Placebo-Controlled Trial in Patients with Parkinson's Disease and Levodopa-Induced Dyskinesias - Antidyskinetic properties of topiramateEUCTR2007-002467-27-GBSalford Royal NHS Foundation Trust
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