EUCTR2007-002467-27-GB进行中（未招募）不适用
Antidyskinetic Properties of Topiramate: A Double-Blind, Placebo-Controlled Trial in Patients with Parkinson's Disease and Levodopa-Induced Dyskinesias - Antidyskinetic properties of topiramate
Salford Royal NHS Foundation Trust0 个研究点开始时间: 2007年11月26日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Patients meet UK Parkinson's Disease Society Brain Bank diagnostic criteria for idiopathic Parkinson's Disease (PD). Patients taking levodopa, with stable levodopa-induced dyskinesias. Stable antiparkinsonian medications for at least one month prior to enrollment.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •Hypersensitivity to topiramate or its excipients. Prior surgery for PD. Hoehn and Yahr score of 5 when 'off'. History of nephrolithiasis, renal impairment, liver disease, glaucoma. Pregnancy or breastfeeding. Premenopausal females and males not using adequate contraception. Use of other antiepileptic drugs, carbonic anhydrase inhibitors, metformin, digoxin, illicit drugs. Dementia as defined by MMSE<24
研究者
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