Effect of induced muscle ischemia on kidney injury
Not Applicable
- Conditions
- Renal dysfunction.Acute renal failure
- Registration Number
- IRCT20180820040838N1
- Lead Sponsor
- Bandare-abbas University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 140
Inclusion Criteria
Age equal or greater than 18 years
Hospitalized patients requiring angiography or PCI
Exclusion Criteria
Patients who did not have consent to participate in the study
Patients with renal dysfunction (GFR <60) based on KDIGO criteria
Pregnant patients
Patients who used nephrotoxic drugs 72 hours before angiography or PCI
Patients who needed an emergency angiography or PCI
Patients with cardiogenic shock, recent cardiac infarction or EF < 50%
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum Creatinine. Timepoint: Before intervention and after intervention daily for 2 days. Method of measurement: AutoAnalyzer.;Urine Neutrophil gelatinase-associated lipocalin (NGAL). Timepoint: Before intervention and 6 hours and 24 hours after intervention. Method of measurement: The enzyme-linked immunosorbent assay (ELISA) kit.;Estimated glomerular filtration rate (eGFR). Timepoint: Before intervention and after intervention daily for 2 days. Method of measurement: Modification of diet in renal diseases (MDRD) GFR Equation.;Acute Kidney Injury (AKI). Timepoint: After intervention. Method of measurement: The 2012 Kidney Disease: Improving Global Outcomes (KDIGO) criteria.
- Secondary Outcome Measures
Name Time Method