A Novel Technique Using Endoscopic Band Ligation for Removal of Long-stalked (>10 mm) Pedunculated Colon Polyps
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 15
- 主要终点
- Procedure time
研究概览
简要总结
Bleeding is the most common complication associated with polypectomy of large pedunculated colonic polyp. Although several techniques have been developed to minimize bleeding, none of these methods has become the gold standard. To prevent post-polypectomy bleeding effectively, the investigators developed and attempted a new endoscopic technique for removal of large long-stalked pedunculated colonic polyps using band ligations. This study aims to evaluate the safety and efficacy of a novel technique using endoscopic band ligation for removal of long-stalked pedunculated colon polyps.
详细描述
A prospective single-center study was conducted. Targeted polyps were large (head size >10 mm) with long stalk length (>10 mm) in the distal colon. After finding target lesions by standard colonoscopy, conventional upper endoscopy with rubber band (endoscopic band ligation, EBL) was applied to squeeze the mid-portion of the stalk to form an omega shape, which had the dual effect of ligation and compression of feeding blood vessels. After strangulation of the stalk, snare polypectomy was performed at the stalk site just above the ligation. The investigators evaluated several parameters, including completeness of resection, procedure time, and complications, including immediate postpolypectomy bleeding, delayed postpolypectomy bleeding, and perforation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Polyps with head >10 mm and stalk length >10 mm;
- •Location at the distal segments of the colon; and
- •Benign features under endoscopic inspection (absence of ulceration and induration or friability).
排除标准
- •Patients who refuse to sign the consent
结局指标
主要结局
Procedure time
时间窗: during the procedure
From approaching the the stalk to snare polypectomy with electrosurgical snare
Rate of perforation
时间窗: 30 days after procedure
endoscopically observed colonic wall penetration, or perforation detected after endoscopy by radiological examination including abdomen CT.
Rate of completed polyp resection
时间窗: Immediately after the intervention
a lesion-free margin with both the lateral and basal tissues free of pathology
Rate of immediate postpolypectomy bleeding
时间窗: during the procedure
pulsating bleeding or oozing lasting more than 60 s immediately after polypectomy or requiring endoscopic intervention.
Rate of delayed postpolypectomy bleeding
时间窗: 30 days after procedure
gross rectal bleeding, bleeding requiring endoscopic or radiological hemostasis, or transfusions requiring surgery
次要结局
未报告次要终点
研究者
Hiun Suk Chae
Professor
Uijeongbu St. Mary Hospital