EUCTR2010-019986-27-ITActive, not recruitingNot Applicable
Breathing disorders in heart failure: high altitude hypoxia as a model to define diagnostic tools, therapeutic strategies and gender related differences. - ND
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Active, not recruiting
- Sponsor
- ISTITUTO AUXOLOGICO ITALIANO
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional clinical trial of medicinal product
Eligibility Criteria
- Sex
- All
Inclusion Criteria
- •- Written informed consent - Patients with symptomatic CHF (NYHA functional class II-III, eitheridiopathic or ischaemic and systolic dysfunction (FE < o = 35%) - Clinically stable condition for > o = 3 months - Optimized CHF pharmacological treatment (all drug classes recommended by recent guidelines for this kind of patients, beta-blockers in particular) and resynchronization therapy whenever needed with preserved spontaneous atrial activity and A-V conduction
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
Exclusion Criteria
- •- Atrial fibrillation - Non optimized pharmacological treatment - Unstable angina - MI, cerebrovascular accident or TIA within the previous three months - Episode of HF decompensation within the previous three months - haemodynamic instability - Conventional indication for pace-maker therapy for AV blocks higher than 1st degree - Clinically relevant pulmonary disease (FEV1<50%, VC<50%, FEV1/FVC<70%) - Inability to perform exercise test, CPAP or oxygen therapy - Use of sedatives, acetazolamide, theophilline and aminophilline
Investigators
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