Injury, inflammatory markers & the exacerbation of confusion: ASCRIBED

Not Applicable

Completed

• Conditions: Dementia patients admitted to acute hospital settings with a hip fracture.; Mental and Behavioural Disorders

• Registration Number: ISRCTN43803769
• Lead Sponsor: niversity of East Anglia

Brief Summary

2019 Protocol article in https://pubmed.ncbi.nlm.nih.gov/31493787/ protocol (added 09/12/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-05-11
• Study Completion: 2022-12-31
• Last Update Posted: 16 October 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 469

Inclusion Criteria

Group 1: Pre-operative acute hip fracture patients with confusion as defined by the Abbreviated Mental Test (England) or 4AT (Scotland):
Inclusion Criteria:
1. Patient must have had a confirmed proximal hip fracture requiring an operation and be aged 60 or older at the time of operation
2. Patient has a pre-operative Abbreviated Mental Test score of 8 or below or 4AT score of 1 or above
3. Patient must be undergoing spinal anaesthesia

Group 2: Pre-operative acute hip fracture patients without confusion as defined by the Abbreviated Mental Test (England) or 4AT (Scotland):
Inclusion Criteria:
1. Patient must have had a confirmed proximal hip fracture requiring an operation and be aged 60 or older at the time of operation
2. Pre-operative Abbreviated Mental Test score of 9 or above or 4AT score of 0
3. Patient must be undergoing spinal anaesthesia

Exclusion Criteria

Group 1 and 2:
1. Decision taken not to have hip surgery
2. Patient has head trauma with bleeding as indicated by a CT scan
3. Patient has confirmed diagnosis of Parkinson’s disease
4. Patient not expected to survive beyond 4 weeks

Study & Design

• Study Type: Observational
• Study Design: Not specified