Effect of Red Meat Intake on Occurrence of Serum Non-transferrin Bound Iron (NTBI)
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 15
- 试验地点
- 1
- 主要终点
- Occurrence of serum non-transferrin bound iron (NTBI) after consumption of red meat
研究概览
简要总结
This study aims to evaluate the effect of red meat intake on occurrence of non-transferrin bound iron (NTBI)
详细描述
During Visit 1, blood samples will be collected to assess iron status. During Visit 2, after an overnight fast, participant will be given a standardized meal (rice and potatoes) with a portion of cooked beef (200 g). Blood samples will be collected right before and 2 hour after the meal for NTBI analysis.
NTBI concentration before and after meal consumption will be compared.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 45 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Apparently healthy male volunteers (21 - 45 years old)
- •C-reactive protein (CRP) < 5 mg/L
排除标准
- •Blood donation or significant blood loss (e.g. surgery) within the past 4 months
- •Regular intake of iron and other nutrient supplements within the past 4 months
- •Regular intake of medication except oral contraceptives
- •Acute or recent inflammatory or infectious symptoms
- •Chronic gastrointestinal disorders or metabolic diseases
- •Coeliac disease or gluten-related disorders
- •Iron deficiency anemia (Hb < 14 g/dL for males) with serum ferritin concentration < 30 ng/mL)
- •Non-iron deficiency anemia (serum ferritin concentration within normal range (30 - 300 ng/mL for males) but low hemoglobin (< 14 g/dL for males)
- •Iron overload conditions (serum ferritin concentration > 300 ng/mL for males)
- •Known hereditary disorders of iron metabolism
结局指标
主要结局
Occurrence of serum non-transferrin bound iron (NTBI) after consumption of red meat
时间窗: 2 hour post meal administration
Blood samples collected 2 h after consumption of red meat will be analyzed for non-transferrin bound iron (NTBI) concentration
次要结局
未报告次要终点
研究者
Thomas Walczyk
Associate Professor
National University of Singapore