Furosemide for prevention 72 hours postpartum hypertension in women with preeclampsia with severe features: A randomized controlled trial
Phase 2
Completed
- Conditions
- Persistent postpartum hypertension in preeclampsia with severe featurePreeclampsia, Postpartum period, Hypertension
- Registration Number
- TCTR20220419002
- Lead Sponsor
- /A
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 80
Inclusion Criteria
Women who's 15 years old or more with preeclampsia with severe features who was undergone termination of pregnancy at 24 weeks' gestation or more
Exclusion Criteria
1.pre-existing hypertension or taking antihypertensive medication
2.hypokalemia
3.history used of diuretic drug
4.unstable vital signs
5.allergy to furosemide or sulfonylurea
6.severe postpartum complication
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Blood pressure at 72 hours postpartum 72 hours postpartum Blood pressure measurement in mmHg,Persistent hypertension at 72 hours postpartum 72 hours postpartum systolic blood pressure 140 mmHg or more OR diastolic blood pressure 90 mmHg or more
- Secondary Outcome Measures
Name Time Method the use of antihypertensive medication at hospital discharge patient's antihypertensive drug at hospital discharge,Milk ejection performance 3 days postpartum milk ejection score (0-4),Hospital stay after termination at hospital discharge number of days,Potassium level 6 hours after 2nd tab administration blood chemistry lab,creatinine level 6 hours after 2nd tab administration blood chemistry lab