Assisted Autogenic Drainage (chest physiotherapy) in South African children with Cystic Fibrosis
Not Applicable
- Conditions
- Fertility-femalecystic fibrosis
- Registration Number
- PACTR201501001016415
- Lead Sponsor
- niversity of Cape Town
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Children between the age of one and eight years of age, suffering from CF, who are being followed up in Red Cross, will be considered for inclusion in the study.
CF has to be diagnosed by sweat testing or genotype analysis.
Exclusion Criteria
- Waiting for a lung/heart-transplantation
- Severe scoliosis or kyphosis
- Osteoporosis
- Recent pneumothorax
- Thoracic or abdominal surgery in the preceding six months
- Emphysema
- Active sarcoidosis
- Prematurely born less than 30 weeks of gestation
- On TB medication
- Untreated asthma
- Not on a treatment regime 2 months prior to enrolment
- non-compliance prior to enrolment
- mother language different from English, Afrikaans or Xhosa
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method umber of hospitalisations in one year;Number of exacerbations in one year, determined by antibiotic prescription and physician diagnosis
- Secondary Outcome Measures
Name Time Method Health Related Quality of Life measured by the EQ-5D-Y;Disease severity measured by the Cystic Fibrosis Clinical Score;Patient's and/or parent's preference;Neurodevelopmental level, measured by the Peabody Developmental Motor Scale 2 and the movement ABC 2;Mortality rate;Annual X-ray scores;Lung function tests in children older than 5 years of age;Weight-for-height (%);Weight-for-height (%);Lung function tests in children older than 5 years of age;Annual X-ray scores