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Clinical Trials/NCT04038333
NCT04038333CompletedNot Applicable

Influenza Vaccination Among Three Recommended Groups in China: Economic Burden, Vaccine Hesitancy, Discrete Choice Experiment, Immunization Records, Willingness to Pay and Financing Strategies

Peking University3 sites in 1 country13,542 target enrollmentStarted: August 1, 2019Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
13,542
Locations
3
Primary Endpoint
economic burden of influenza-like illness (ILI)

Study Overview

Brief Summary

This trial focuses on influenza vaccination among three recommended groups in China. Data concerning the economic burden of influenza-like illness (ILI), vaccine hesitancy, discrete choice experiment, immunization records and willingness to pay for vaccines will be collected via questionnaires, and the financing strategies of influenza vaccines in China will be further analyzed. Besides, the knowledge, attitude/belief and practice (KAP) of medical staff will also be asked in a supplementary questionnaire.

Detailed Description

This trial focuses on influenza vaccination among three recommended groups in China, including children (aged between 6 to 59 months), the elderly (aged 60 years old or above), and adult patients with chronic diseases (aged below 60 years old).

The questionnaires will collect data on the economic burden of influenza-like illness (ILI), vaccine hesitancy, discrete choice experiment, immunization records and willingness to pay for vaccines, and the financing strategies of influenza vaccines in China will be further analyzed accordingly.

Besides the three recommended groups, vaccination and health care personnel will also be asked about their knowledge, attitude/belief and practice (KAP) in a supplementary questionnaire.

Study Design

Study Type
Observational
Observational Model
Case Only
Time Perspective
Cross Sectional

Eligibility Criteria

Ages
6 Months to — (Child, Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • (For children group) children aged between 6 to 59 months.
  • (For the elderly group) the elderly aged 60 years old or above.
  • (For chronic disease patient group) adult patients with chronic diseases aged below 60 years old.
  • (For medical staff) general practitioners and vaccination staff.
  • Interviewees with informed consent.

Exclusion Criteria

  • Those cannot be surveyed for physical reasons.
  • Those with communication barriers.
  • Those who do not agree to participate in the survey.

Outcomes

Primary Outcomes

economic burden of influenza-like illness (ILI)

Time Frame: 2019.08-2019.09

Questions were designed in the questionnaire to ask the economic burden of influenza-like illness (ILI), including direct and indirect costs. Specifically, direct costs include inpatient cost (both out-of-pocket and reimbursed, range 0-100,000), hospitalization cost (both out-of-pocket and reimbursed, range 0-500,000), drug cost (both out-of-pocket and reimbursed, range 0-100,000), transportation cost (range 0-100,000), accommodation cost range (0-100,000) and food cost (range 0-100,000). Indirect cost include missed working days of the patients and their relatives/friends.

willingness to pay

Time Frame: 2019.08-2019.09

Questions were designed in the questionnaire to ask interviewees' willingness to pay for influenza vaccination. A value between 0 and 150 RMB will be randomly generated, and ask the respondent whether he or she is willing to pay for influenza vaccination. For example, one is asked "Would you like pay 102 for influenza vaccination?" If the answer is "Yes", then he or she will be asked "Would you like pay 112 for influenza vaccination?" If the answer is "No", then he or she will be asked "Would you like pay 92 for influenza vaccination?" The willingness to pay is then settled and recorded. Moreover, the proportion of vaccination cost paid by individuals will be asked (if others will be paid by health insurance and the government).

Secondary Outcomes

  • financing strategies(2019.08-2019.09)
  • discrete choice experiment(2019.08-2019.09)
  • vaccine hesitancy and immunization records(2019.08-2019.09)

Investigators

Sponsor
Peking University
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Hai Fang

Professor

Peking University

Study Sites (3)

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