Bioavailability of Anthocyanins of Blue Potatoes as Compared With Bilberries
Not Applicable
Completed
- Conditions
- Postprandial Glycemia
- Interventions
- Other: Dietary intervention
- Registration Number
- NCT02005796
- Lead Sponsor
- University of Turku
- Brief Summary
In this study, the postprandial glycemia and insulinemia caused by boiled potato with blue-fleshed or yellow-fleshed tubers, or a gel prepared with bilberries and potato starch, is studied in healthy males. Additionally, the appearance and metabolism of the flavonoids and their metabolites is studied in plasma and urine.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 14
Inclusion Criteria
- Age 18-45
- Male
- No regular medication
- No participation in a drug trial or blood donation within 2 months
- Non-smoker
- Signs informed consent
- Body mass index 18.5-27 kg/m2
- Fasting plasma cholesterol < 5.5 mmol/l
- Fasting plasma triacylglycerols < 2.6 mmol/l
- Fasting plasma glucose 4-6 mmol/l
- blood pressure <140/80 mmHg
- hemoglobin>130 g/l
- Fasting plasma alanine amino transferase (ALAT) <60 U/l (normal liver function)
- Fasting plasma thyroid-stimulating hormone (TSH) 0.4 - 4.5 mU/l (normal thyroid function)
- Fasting plasma creatinine <118 µmol/l (normal kidney function)
Exclusion Criteria
- Regular smoking
- Alcohol abuse
- Regular medication
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Yellow-fleshed potato tubers Dietary intervention Intervention: Steam cooked mashed potato tubers Blue-fleshed potato tubers Dietary intervention Intervention: Steam cooked mashed potato tubers Bilberries and potato starch Dietary intervention Intervention: A gel boiled with bilberries and potato starch
- Primary Outcome Measures
Name Time Method Plasma glucose concentration 20min, 40min, 60min, 90min, 120min, 180min, 240min Plasma insulin concentration 20min, 40min, 60min, 90min, 120min, 180min, 240min
- Secondary Outcome Measures
Name Time Method Concentrations and quality of flavonoid color compounds or their metabolites in plasma and urine (NMR-measurement) 20min, 40min, 60min, 90min, 120min, 180min, 240min Concentrations and quality of flavonoid color compounds or their metabolites in plasma and urine (HPLC-measurement) 20min, 40min, 60min, 90min, 120min, 180min, 240min
Trial Locations
- Locations (1)
Department of Biochemistry, University of Turku
🇫🇮University of Turku, Turku, Finland