Glucose Response From Antioxidant Rich Potato Chips
- Conditions
- Glycemic Response
- Interventions
- Other: CrackersOther: Mountain Rose potato chipsOther: Purple Majesty potato chipsOther: White potato chips
- Registration Number
- NCT02927015
- Lead Sponsor
- Purdue University
- Brief Summary
Assess impact of potato phytochemical on post-prandial gastric emptying and glucose release from products in a pilot human study.
- Detailed Description
Preclinical data obtained using an Caco-2 intestinal cell model and enzyme assays suggest phenolic-rich potato extracts decrease intestinal glucose transport. The aim is to determine if these effects extend to the the an in vivo situation. Specifically, the glycemic response following consumption of phenolic rich pigmented potatoes compared to white potatoes with lower phenolic content will be measured. Gastric emptying will also be measured to show the effects are in fact due to rate of carbohydrate digestion and intestinal glucose transport and not gastric emptying rate.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 11
- BMI 18-25 non-smoker
- BMI outside 18-25 smoker previous gastrointestinal disease or other disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Crackers Crackers Crackers Mountain Rose potato chips Mountain Rose potato chips Mountain Rose potato chips Purple Majesty potato chips Purple Majesty potato chips Purple Majesty potato chips White potato chips White potato chips White potato chips
- Primary Outcome Measures
Name Time Method Blood Glucose up to 2 hours blood taken at 10, 20, 30, 60, and 120 minutes by finger prick
Gastric emptying up to 4 hours Breath Hydrogen concentrations will be measured every 15 minutes for 4 hours
- Secondary Outcome Measures
Name Time Method