Functional MRI and MRA in Migraine With Aura

Glostrup University Hospital, Copenhagen1 site in 1 country80 target enrollmentDecember 2010

ConditionsMigraine With Aura

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Migraine With Aura
Sponsor: Glostrup University Hospital, Copenhagen
Enrollment: 80
Locations: 1
Last Updated: 14 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Patients who report that exposure to bright light or strenuous physical activity will induce migraine aura will be provoked using one or both of these methods. Followingly the patients will be examined by functional MRI. Íf the patients develop migraine headache, MR angiography will be performed as well. The primary study hypothesis is that the functional MRI signal will show features similar to those of the electrophysiological phenomenon of cortical spreading depression.

Registry

clinicaltrials.gov

Start Date

December 2010

End Date

TBD

Last Updated

14 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Glostrup University Hospital, Copenhagen

Eligibility Criteria

Inclusion Criteria

•Diagnosed with migraine with aura as defined by The International Classification of Headache Disorders 2
•Age between 18 and 80 years both inclusive
•Reports that bright light or strenuous physical activity may trigger migraine aura

Exclusion Criteria

•Contraindications towards exposure to photostimulation or strenuous exercise
•Body weight above 130 kg
•Pregnant or lactating females
•Contraindications towards MRI scanning
•History or clinical signs of: cardiovascular disease, psychiatric disease, substance abuse or any symptom or disease considered relevant by the examining physician.