NCT01471314Unknown不适用
Functional MRI and MR Angiography Used in Spontaneous Migraine
Glostrup University Hospital, Copenhagen1 个研究点 分布在 1 个国家开始时间: 2011年11月15日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 试验地点
- 1
研究概览
简要总结
The purpose of this study is to examine migraineurs during spontaneous migraine attacks without aura, using high resolution magnetic resonance imaging (MRI), to study following:
- Changes in resting state blood-oxygenation-level-dependent-signal (BOLD-signal) using functional MRI (fMRI).
- Changes in circumferences of intra- and extracranial arteries using MR-angiography (MRA).
- Changes in regional and global cerebral blood flow (CBF) using the arterial spin labeling (ASL) method.
Moreover to perform diffusion tensor imaging (DTI) scans during spontaneous migraine attacks.
The migraine specific drug sumatriptan will be given to relieve pain and the effect will be registered using MRA and fMRI if possible.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Migraine without aura according to IHS criteria.
排除标准
- •Other primary headaches.
- •Tension-type headache more than 5 days/month.
- •Use of anti-pain medication before the scanning on the examination day.
- •Pregnant or nursing women.
- •Contraindication for MR scan.
- •Anamnestic or clinical signs of cardiovascular or cerebrovascular disease, unregulated psychiatric disease or drug misuse.
- •Other clinical conditions assessed by the examining doctor.
研究者
Faisal Mohammad Amin
MD, PhD student
Glostrup University Hospital, Copenhagen
研究点 (1)
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