Comparison of oral Azithromycin versus oral Doxycycline in children with Scrub Typhus A randomized controlled study

This  prospective randomized controlled study will be performed in the paediatric ward of Sri manakula vinayagar medical college and hospital a tertiary care hospital in Puducherry after the approval of research committee and institutional ethics committee.Children who fulfill the criteria will be included in the study after the informed and written consent is being obtained from the parents

Enrolled children will be randomized using computer generated randomized sequence into two groups by using sequentially numbered sealed envelopes which will be opened by the post graduate or intern and the intervention written will be administered to the patient.children allocated in group A receive oral Azithromycin  and children  allocated in group B receive oral doxycycline .In case of any deterioration of the patient clinically or no improvement in the patient even after 72 hours after treatment patient was classified as treatment fail and alternative treatment will be started to the patient or if any alternative diagnosis was concluded because of other investigations sent they should be medically managed with the respective drugs and they will  be excluded from the study.

Aprincipal investigator will assess the time taken for the defervescence of fever and duration of hospital stay between Azithromycin and doxycycline group .