Assessment of Right Ventricular Function After Acute Pulmonary Embolism Using Speckle Tracking Echocardiography
试验速览
- 阶段
- 不适用
- 入组人数
- 68
- 主要终点
- improve management of acute pulmonary embolism
研究概览
简要总结
- To asses regional RV function in patients presented with acute pulmonary embolism using speckle tracking echocardiography
- To evaluate its relationship to long term mortality.
详细描述
Pulmonary embolism (PE) is the third most common cardiovascular cause of death after myocardial infarction and stroke . The incidence of PE has been increasing ,with significant associated mortality; a recent registry of PE patients reported a mortality rate > 10% at 30 days. There are a number of emerging contemporary PE therapies, including thrombolysis, catheter intervention and surgery. Early and accurate identification of PE in patients is therefore critical. A transthoracic echocardiogram (TTE) may help when there is a clinical suspicion for PE, and its use in confirmed PE is widely recommended . A number of right atrial (RA) and right ventricular (RV) parameters have been shown to be abnormal in patients with PE . In addition, RA and RV enlargement portends a worse prognosis in these patients .
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 70 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •clinical diagnosis of acute pulmonary embolism
- •Age: 20 - 70 years.
排除标准
- •coronary artery disease
- •patient of Atrial fibrillation.
- •Patient of impaired RV function due to chest disease (Cor-pulmonale)
- •patient with impaired Ejection fraction (EF) <50%
- •Moderate to severe valvular heart disease.
- •Atrio-ventricular conduction disturbance.
- •Poor echogenicity
结局指标
主要结局
improve management of acute pulmonary embolism
时间窗: baseline
comparison between speckle tracking echocardiograpgy and conventional echocardiography in pulmonary embolism
次要结局
未报告次要终点
研究者
Mahmoud Said Rashwan
doctor
Assiut University
