Early Neuromuscular Electrical Stimulation in Critically Ill Trauma Patients

Not Applicable

• Conditions: Multiple TraumaIntensive Care UnitsMuscle, SkeletalElectric Stimulation; C26.640; N02.278.388.493; A02.633.567; E05.723.402

• Registration Number: RBR-2dbzdy
• Lead Sponsor: niversidade de Brasilia - Programa de Pós-Graduação em Ciências e Tecnologias em Saúde

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-08-23
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Data analysis completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Major trauma patients were assessed for eligibility within the first 24 hours after hospital admission. Adults older than 18 years old with invasive mechanical ventilation were included.

Exclusion Criteria

pregnancy; stroke; previous neuromuscular disease; suspicion of brain death; lower limb amputation, fracture or skin lesion that restrained ultrasound evaluation.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Expected: Mean change in muscle quality (echogenicity), assessed by muscle ultrasound, based on a minimal variation of 15% in pre and post intervention; mean change in size (thickness), assessed by muscle ultrasound, based on a minimal variation of 8% in pre and post intervention.;Observed: mean change in muscle quality (echogenicity), assessed by muscle ultrasound, of 32% in pre and post intervention; mean change in size (thickness), assessed by muscle ultrasound, based on a minimal variation of 15% in pre and post intervention.

Secondary Outcome Measures

Name	Time	Method
Expected: smaller decrease on circulating levels of IGF-I at intervention group (15%) compared to control group (30%).;Observed: Smaller decrease on circulating levels of IGF-I at intervention group (18%) compared to control group (45%).