NL-OMON55962
Recruiting
Not Applicable
Early detection of diastolic dysfunction and heart failure with preserved ejection fraction - EARLY-HFPEF
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Vrije Universiteit Medisch Centrum
- Enrollment
- 900
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Males and females aged 50\-75 years;
- •duration of T2DM of at least 1 year (defined on the basis of previous diagnosis
- •and/or treatment with hypoglycaemic agents);
- •with informed consent to be contacted for future research;
- •able to provide a written consent form.
Exclusion Criteria
- •1\. Advanced diabetes complications (like proliferative retinopathy, disabling
- •polyneuropathy, or stages IV\-V diabetic nephropathy). 2\. Cardiac comorbidity:
- •a) Valvular heart disease requiring surgery or intervention, or within 3 months
- •after valvular surgery or intervention. b) Hypertrophic obstructive
- •cardiomyopathy. c) Acute myocarditis, sarcoidosis, amyloidosis, Takotsubo
- •cardiomyopathy. d) Post\-heart transplant cardiomyopathy. e) Chronic HFrEF (a LV
- •EF of \< 50% assessed within 12 months prior to randomization). f) Clinical
- •diagnosis of HFpEF. g) Tachycardia\-induced cardiomyopathy and/or uncontrolled
- •tachyarrhythmia. h) Acute coronary syndrome (unstable angina, non\-ST elevation
- •myocardial infarction \[NSTEMI]or ST elevation myocardial infarction \[STEMI]) or
Outcomes
Primary Outcomes
Not specified
Similar Trials
Recruiting
Not Applicable
We will identify biomarkers of diastolic dysfunctiodiastolic dysfunctionJPRN-UMIN000033290Dokkyo Medical University300
Completed
Not Applicable
Early detection of cardiovascular dysfunction and health behaviours in the young with type 2 diabetesType 2 diabetesNutritional, Metabolic, EndocrineISRCTN60207691niversity Hospitals of Leicester NHS Trust (UK)40
Completed
Not Applicable
Biomarkers and (pre-)diastolic dysfunction in the healthy elderlyDiastolic heart failureHeart failure with preserved ejection fraction10019280NL-OMON45721niversitair Medisch Centrum Groningen100
Not yet recruiting
Not Applicable
The patients undergoing routine endoscopic urological surgeries are choosen and are subjected to assessment of left ventricular diastolic function and later are assessed for intra-operative haemodynamic changes and intra-operative and post-operative complicationsHealth Condition 1: N998- Other intraoperative and postprocedural complications and disorders of genitourinary systemCTRI/2020/01/022911Indira Gandhi Medical College
Completed
Not Applicable
Early Diagnosis of Diastolic Dysfunction and Reliability of DSE in Detecting Stress Diastolic DysfunctionDiastolic DysfunctionNCT00998205University of Missouri-Columbia16