MIS-C treatment study
Not Applicable
- Conditions
- Health Condition 1: U071- COVID 19 virus identified
- Registration Number
- CTRI/2023/08/056383
- Lead Sponsor
- ICMR-NIRT
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Children and Adolescents who meet the criteria for CDC case definition of Multisystem inflammatory Syndrome
Exclusion Criteria
1. Caretakers and children who have not consented 2. Children admitted to PICU for conditions other than MIS-C
3. Children on long term steroid and immunosuppressant therapy
4. Children with Adrenocortical insufficiency
5. Children with congenital or acquired immunodeficiency
6. Children who have received steroids before enrolment into study
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The expected results of this study are likely to help our understanding of MIS-C & the different treatment options, which might help us to formulate a protocol or guidance for the management of MIS-C.Timepoint: â?¢Median cytokine levels (various cytokines) at day 0, day 2-3, & at day 5-7 <br/ ><br>â?¢Reduction in proportion of cytokine levels in each group <br/ ><br>
- Secondary Outcome Measures
Name Time Method â?¢Correlation of cardiac markers with disease manifestation <br/ ><br>â?¢Correlation of Gene polymorphisms with disease manifestation <br/ ><br>Timepoint: at baseline & discharge