ST Elevation in Acute Chest Pain; Could Measurement of Lipoprotein-associated Phospholipase A2 (Lp-PLA2) be Helpful to the Clinician?

Completed

• Conditions: Acute Chest Syndrome

• Registration Number: NCT01041339
• Lead Sponsor: Alexhander Izhaki

Brief Summary

A blood test (2-3 cc peripheral venous blood) drawn /used from already available required lab tests to distinguish between pericarditis accompanied with electrocardiogram (ECG) signs mimicking infarction. A test of clinical potential if proven to be able to support either origin of acute chest pain etiology.

Detailed Description

Too many times young patients presenting with acute chest pain are referred to invasive angiography or treated with anticoagulation therapy a measure of detrimental effect in those inflicted with acute pericarditis.

A simple blood test (the PLAC test) may have some value in aiding rapid diagnosis saving need for cath.

Study Timeline

• Study First Submitted: 2009-12-30
• Study First Submitted QC: 2009-12-30
• Study First Posted: 2009-12-31
• Study Start: 2010-01
• Status Verified: 2011-06
• Primary Completion: 2011-11
• Study Completion: 2012-01
• Last Update Submitted: 2015-12-13
• Last Update Posted: 2015-12-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• acute chest pain
• acute ST elevation
• elevated troponin I

Exclusion Criteria

• patients with recent (> 24 hour chest pain) myocardial infarction
• refusing to provide blood samples

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

The E.Wolfson MC; 🇮🇱 Holon, Israel