to compare dexmedetomidine versus nitroglycerine as a hypotensive agent causing less blood loss in posterior fixation surgery of spine.
- Conditions
- age 18-65yrs ,ASA I and II
- Registration Number
- CTRI/2018/04/013065
- Lead Sponsor
- Vardhaman Mahavir Medical College And Safdarjung Hospital
- Brief Summary
Thisstudy is planned to compare dexmedetomidine with nitroglycerine as a hypotensiveagent during posterior fixation surgery of spine in terms of
(1)intraoperative haemodynamic changes and blood loss
(2)the recovery characteristics and side effects .
HYPOTHESIS-Dexmedetomidineis superior than nitroglycerine as a hypotensive agent in patients undergoingposterior fixation surgery of spine.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- All
- Target Recruitment
- 40
1.Patients of age 18-65yrs undergoing posterior fixation of spine surgery under general anaesthesia 2.ASA I and II.
1.Patients with hypertension 2.Patients with history of significant systemic disorders ( like cardiovascular, respiratory , central nervous system, hepatic and renal ) 3.Patients with bleeding disorders.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare intra-operative haemodynamic changes and blood loss with infusion of dexmedetomidine and nitroglycerine in patients undergoing posterior fixation surgery of spine. intra-operative
- Secondary Outcome Measures
Name Time Method To compare the recovery characteristics and side effects of both these drugs in patients undergoing posterior fixation surgery of spine. intra-operative
Trial Locations
- Locations (1)
vmmc and safdurjung hospital,new delhi
🇮🇳South, DELHI, India
vmmc and safdurjung hospital,new delhi🇮🇳South, DELHI, IndiaCHANDRIKA PRIYADARSHINIPrincipal investigator8882123216mary.chandrika@gmail.com