A multicentre observational study to look into the practise of using non invasive ventilation in COVID-19 patients requiring ICU admission for respiratory support and their outcome in terms of their failure rate as well as exploiting the HACOR scale to predict NiV failure.

Not Applicable

• Conditions: Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere

• Registration Number: CTRI/2021/02/031409
• Lead Sponsor: DR Saurav Sutradhar

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

All the patients 18 years & above of age, suspected or tested positive for SARS-COV2 (RtPCR/RAT) being admitted to the

Intensive care with de novo acute hypoxemic respiratory failure defined as recent onset respiratory failure as evidenced by a P/F

ratio of less than equal to 300 mmHg, signs of respiratory distress along with the

presence of pulmonary infiltrates on chest images, in the absence

of chronic cardio-respiratory diseases, including extubation failure with hypoxemia and, in whom NiV was initiated and administered

for at least 30 minutes. The underlying condition deemed to have caused DNAHRF and the reason for NiV initiation was adjudged

by the treating Critical care physician and documented. ARDS will be diagnosed as per the BERLIN criteria.

Exclusion Criteria

All patients with history of chronic cardio-respiratory illness as well as those who are home O2/Niv user.

Patients who have failed extubation as well as those refusing NiV due to intolerance or with do not intubate orders.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. NiV failure rate <br/ ><br>2. Patient Outcome in terms of death or discharge from ICU among <br/ ><br> patients with Early and Late groups of NiV failure. <br/ ><br>Timepoint: Patients parameters will be assessed at baseline before Non invasive ventilation (NiV) initiation, thereafter at 1 hour, 24 hours and at 48 hours post NiV usage. <br/ ><br>The patient will be followed for a maximum period of 28 days in the ICU. <br/ ><br>

Secondary Outcome Measures

Name	Time	Method
tilasation of HACOR scale to predict NiV failureTimepoint: Patients bed side parameters will be assessed at baseline prior to NiV usage and thereafter at 1 hour, 24 hours and 48 hours of NiV initiation. <br/ ><br>