A Pilot Study on Efficacy of Transconjunctival Dexamethasone in treatment of upper lid retraction in thyroid eye disease

• Conditions: Efficacy of Transconjunctival Dexamethasone in treatment of upper lid retraction in thyroid eye disease; thyroid eye disease; transconjunctival; dexamethasone; lid retraction

• Registration Number: TCTR20240703001
• Lead Sponsor: Faculty of Medicine Siriraj Hospital, Mahidol University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-07-03
• Last Update Posted: 19 August 2024
• Study Completion: 2025-06-30

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

1. Over 18 years old.
2. Patients with thyroid retinopathy have a upper lid retraction less than 1 year, the distance from the center of cornea to the upper eyelid (margin reflex distance1) more than 5 millimeters.
3. Thyroid hormone levels Free T3 and/or Free T4 were within normal at least 3 months before participating in this study.
4. Not smoke or if smoked must abstain more than 6 months before participating in this study.

Exclusion Criteria

1. Have eyelid surgery in the past 6 months before or plan to surgery during participate in this study.
2. Have eye orbital surgery in the past 6 months before or plan to surgery during participate in this study.
3. Have receive treatment with triamcinolone or dexamethasone injection in eyelid before.
4. Have received treatment with other eyelid injections in the past 6 months before.
5. Intra ocular pressure more than 21 mmHg or visual field abnormality or any glaucoma suspect.
6. Smoked in during this study.
7. Have eyelid infection.

Study & Design

• Study Type: Observational
• Study Design: Not specified