Proximal Intestinal Obstruction Syndrome (PIOS) in a Patient With Cystic Fibrosis: A New Syndrome

Completed

• Conditions: Cystic Fibrosis; Distal Intestinal Obstruction Syndrome; Bowel Obstruction

• Registration Number: NCT04613063
• Lead Sponsor: Tecnologico de Monterrey

Brief Summary

A case of a patient with cystic fibrosis with bowel obstruction due to a proximal intestinal obstruction syndrome (PIOS) is presented.This syndrome can be diagnosed with the DIOS definition, with the only distinction of a more proximal location in the gastrointestinal tract, such as the stomach, the duodenum, or the jejunum.

Detailed Description

Distal Intestinal Obstruction Syndrome is a rare complication in cystic fibrosis patients characterized by the accumulation of viscid fecal material, combined with sticky mucous secretions located in the distal ileum, adhered to the intestinal wall. Only few cases have been reported in the literature.

Study Timeline

• Status Verified: 2020-10
• Study Start: 2020-10-19
• Primary Completion: 2020-10-20
• Study Completion: 2020-10-21
• Study First Submitted: 2020-10-21
• Study First Submitted QC: 2020-10-27
• Last Update Submitted: 2020-10-27
• Study First Posted: 2020-11-03
• Last Update Posted: 2020-11-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 1

Inclusion Criteria

• Adult >18 years
• Cystic fibrosis
• Bowel obstruction

Exclusion Criteria

• Pediatric patient <18 years
• Unknown cause of bowel obstruction

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Bowel obstruction in a patient with cystic fibrosis	3-6 days	A 45 year old patient with cystic fibrosis presented with bowel obstruction. Image studies were performed, without identifying a specific cause of the bowel obstruction. The patient was transferred to surgery.

Trial Locations

Locations (1)

Escuela Nacional de Medicina, Tecnologico de Monterrey; 🇲🇽 Monterrey, Nuevo Leon, Mexico