MedPath

Entero Therapeutics

Ownership
-
Employees
9
Market Cap
-
Website
Introduction

First Wave Biopharma, Inc. is a clinical stage biopharmaceutical company, which engages in the research and development of non-systemic therapies for the treatment of gastrointestinal diseases. The firm involves in therapeutic development pipeline populated with multiple clinical stage programs built around its proprietary technologies, such as Niclosamide, an oral small molecule with anti-viral and anti-inflammatory properties, and the biologic Adrulipase, a recombinant lipase enzyme designed to enable the digestion of fats and other nutrients. Its programs include FW-UP, FW-UC, FW-CD,FW-COV, FW-ICI-AC, MS1819, COVID-19 GI infections, and FW-EPI. The company was founded on January 30, 2014 and is headquartered in Boca Raton, FL.

Clinical Trials

10

Active:0
Completed:4

Trial Phases

3 Phases

Early Phase 1:1
Phase 1:1
Phase 2:8

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (10 trials with phase data)• Click on a phase to view related trials

Phase 2
8 (80.0%)
Early Phase 1
1 (10.0%)
Phase 1
1 (10.0%)

Study to Assess an Enteric Microgranule Formulation of Adrulipase in Patients With Cystic Fibrosis

Phase 2
Completed
Conditions
Cystic Fibrosis
Exocrine Pancreatic Insufficiency
Interventions
First Posted Date
2023-02-08
Last Posted Date
2024-04-11
Lead Sponsor
Entero Therapeutics
Target Recruit Count
13
Registration Number
NCT05719311
Locations
🇺🇸

Central Florida Pulmonary Group, Orlando, Florida, United States

🇺🇸

The Cystic Fibrosis Institute, Northfield, Illinois, United States

🇺🇸

Childrens Lung Specialists, Las Vegas, Nevada, United States

Safety and Efficacy of Niclosamide in Patients With COVID-19 With Gastrointestinal Infection

Phase 2
Terminated
Conditions
Covid19
Interventions
Drug: Placebo
First Posted Date
2021-04-26
Last Posted Date
2024-10-08
Lead Sponsor
Entero Therapeutics
Target Recruit Count
166
Registration Number
NCT04858425
Locations
🇺🇸

Central Alabama Research, Birmingham, Alabama, United States

🇺🇸

Midland Florida Clinical Research Center, LLC, DeLand, Florida, United States

🇺🇸

New Generation Medical Research, Hialeah, Florida, United States

and more 22 locations

Study of Latiglutenase in T1D/CD Patients

Phase 2
Terminated
Conditions
Celiac Disease
Interventions
Drug: Placebo
First Posted Date
2021-04-09
Last Posted Date
2024-08-05
Lead Sponsor
Entero Therapeutics
Target Recruit Count
13
Registration Number
NCT04839575
Locations
🇺🇸

Stanford University, Palo Alto, California, United States

Niclosamide in COVID-19

Phase 2
Withdrawn
Conditions
Covid19
Interventions
First Posted Date
2020-09-09
Last Posted Date
2022-02-21
Lead Sponsor
Entero Therapeutics
Registration Number
NCT04542434

Niclosamide In Moderate COVID-19

Phase 2
Withdrawn
Conditions
COVID
Interventions
First Posted Date
2020-06-18
Last Posted Date
2022-02-21
Lead Sponsor
Entero Therapeutics
Registration Number
NCT04436458
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News

Entero Therapeutics to License AI-Powered Clinical Trial Compliance Tech from Data Vault

Entero Therapeutics will license Data Vault's QOLPOM and FotoDigm platforms to enhance clinical trial compliance, particularly for its Phase 3 latiglutenase trial.

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