Retrospective Study to Investigate Total Intravenous Anaesthesia (TIVA) With Propofol on Postoperative Pain and Side Effects After Surgery
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- pain score
研究概览
简要总结
Propofol is a commonly used anaesthetic with rapid recovery and less side effects and total intravenous anaesthesia (TIVA) with propofol is a common technique now. The reduction on certain serum pro- inflammatory cytokines may lead to more smooth post- surgical recovery.
Recent case report proved the analgesic effect of propofol infusion. However other animal and clinical studies showed controversial result.
The aim of this retrospective study is to investigate the postoperative analgesic effects and side effects of intraoperative TIVA with propofol in patient undergoing surgery at Queen Mary Hospital, Hong Kong between 2014 to 2016.
详细描述
Objectives:
- To investigate the analgesic effects of propofol.
- To evaluate the effect of propofol on postoperative adverse events.
Methods:
Retrospective audit.
Data Collection:
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Anaesthetic records and acute pain service records of patient undergone surgery between 2014 to 2016 in Queen Mary Hospital would be retrieved from the computer.
排除标准
- •Essential data were missing.
- •Patient participating in other research projects.
- •Changes in postoperative pain management technique.
- •Patients could not be assessed post-operatively for pain (i.e. post-operative IPPV)
研究组 & 干预措施
Group TIVA
Patient undergoing surgery at Queen Mary Hospital, Hong Kong between 2014 to 2016 using intraoperative TIVA with propofol.
干预措施: Propofol (Drug)
Group GA
Patient undergoing surgery at Queen Mary Hospital, Hong Kong between 2014 to 2016 using general anaesthesia methods other than intraoperative TIVA with propofol.
干预措施: general anaesthesia (Procedure)
结局指标
主要结局
pain score
时间窗: up to postoperative day 3
pain score using numeral rating scale
次要结局
- analgesic consumption(up to postoperative day 3)
研究者
Wong Sau Ching Stanley
Clinical Assistant Professor
The University of Hong Kong