A Comparison of Propofol Based Total Intravenous Anesthesia and Sevoflurane Based Balanced Anesthesia on Renal Protection During Lung Transplantation Under Extracorporeal Membrane Oxygenation - A Prospective, Randomized Trial

Phase 4

Completed

• Conditions: Patients Undergoing Lung Transplantation Under Extracorporeal Membrane Oxygenation

• Registration Number: NCT02009280
• Lead Sponsor: Yonsei University

Brief Summary

The aim of this study is to investigate whether propofol based total intravenous anesthesia reduces incidence of acute kidney injury following the lung transplantation under extracorporeal membrane oxygenation

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2013-11
• Study First Submitted: 2013-12-08
• Study First Submitted QC: 2013-12-08
• Study First Posted: 2013-12-11
• Primary Completion: 2016-07
• Study Completion: 2016-07
• Status Verified: 2016-08
• Last Update Submitted: 2016-08-16
• Last Update Posted: 2016-08-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Sixty adults undergoing lung transplantation under extracorporeal membrane oxygenation

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Exclusion Criteria

• Patient having propofol allergy, BMI > 30 kg/m2

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Comparison of the incidence of acute kidney injury between the lung transplantation recipients under propofol based anesthesia and inhalation based anesthesia	Postoperative 48 hours	Developement of the acute kidney injury is determined by Plasma neutrophil gelatinase-associated lipocalin (NGAL), Cystatin C, and Creatinine

Trial Locations

Locations (1)

Department of Anesthesiology and Pain Medicine, Severance Hospital, Yonsei University Health System; 🇰🇷 Seoul, Korea, Republic of