Muscle Quality and Subcutaneous Adipose Tissue in the Rectus Femoris and Rectus Abdominis Muscles: Ultrasound Evaluation and Functional Correlation in Older Adults
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Ultrasound Assessment of the Rectus Femoris Muscle
研究概览
简要总结
The goal of this observational, cross-sectional study is to examine the relationship between body composition and muscle quality in women over the afe of 65. The main question it aims to answer is:
How are ultrasound-based measurements of muscle and fat tissue related to functional performance in older women?
详细描述
In this observational and cross-sectional study, researchers will use ultrasound imaging and physical performance tests to evaluate muscle thickness, subcutaneous fat thickness, abdominal circumference, handgrip strength, and functional performance. These measurements will help identify muscle and fat distribution profiles associated with higher functional risk in older adults.
This study aims to contribute to the understanding of sarcopenic obesity and muscle quality in aging, with the ultimate goal of improving preventive physiotherapy strategies and promoting healthy aging.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Aged ≥ 65 years and living in the community.
- •Female sex.
- •Enrolled as a participant in PReGe program.
排除标准
- •Recent surgery (<6 months) involving the abdomen or lower extremities.
- •Presence of methal prostheses or implants in the thigh or abdoinal region.
- •Diagnosed neuromuscular disease (e.g., myopathies, advanced Parkinson's disease.)
- •Musculoskeletal disorders that impair basic mobility or prevent functional testing.
- •Acute illness or clinical decompensation at the time of assessment.
- •Unintentional weight loss > 5 kg within the past month (suggestive of cachexia risk).
- •Presence of active abdominal hernias or severe diastasis recti.
结局指标
主要结局
Ultrasound Assessment of the Rectus Femoris Muscle
时间窗: At a single assessment visit
The rectus femoris muscle was assessed using B-mode ultrasound imaging, following SARCUS group recommendations. Participants were positioned supine for 5 minutes prior to imaging to ensure fluid redistribution. A linear transducer (12 MHz) was used with neutral probe angle and minimal pressure. The anatomical landmark was the midpoint between the greater trochanter and the upper pole of the patella. Measurements included muscle thickness, pennation angle, fascicle length, echo intensity, cross-sectional area, and subcutaneous fat thickness. Images were taken in both transverse and longitudinal planes. Three measurements were taken per view to ensure accuracy.
Ultrasound Assessment of the Rectus Abdominis Muscle
时间窗: At a single assessment visit
The rectus abdominis muscle was assessed using the same ultrasound equipment and imaging protocol as for the rectus femoris. The anatomical reference point was located 3 cm lateral to the umbilicus, as per SARCUS group guidance. Images were acquired in both transverse and longitudinal planes. Measurements included muscle thickness, echo intensity, anatomical cross-sectional area, and subcutaneous fat thickness. Three measurements were taken per view to ensure reliability.
次要结局
- Grip strength test(At a single assessment visit)
- Chair stand test(At a single assessment visit)
- Body Mass Index (BMI)(At a single assessment visit)
- Short Physical Performance Battery (SPPB)(At a single assessment visit)
- Gait speed(At a single assessment visit)
- Timed Up and Go (TUG)(At a single assessment visit)
研究者
Luis Polo Ferrero
Associate Professor of Physical Therapy at the University of Salamanca
University of Salamanca