Vitamin K status in Children with Osteogenesis Imperfecta

Completed

• Conditions: Brittle bone disease; 10028396

• Registration Number: NL-OMON48934
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 22 July 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 80

Inclusion Criteria

Patients:
- Genetically confirmed Osteogensis Imperfecta (O.I.) type I-IV
- age 0-18 years
- at least once a year bisphosphonate infusions as part of regular care,
Controls:
- no O.I.
- age 0-18 years
- needing orthopaedic or ear, nose, throat surgery so that they will already
get an infusion line.

Exclusion Criteria

Patients:
- Not genetically confirmed O.I. type I-IV
- using vitamin K supplementation, Controls:
- known disease affecting vitamin K or bone turnover
- using vitamin K supplementation

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified