Possible Association between Behcet Disease and Periodontal Diseases

Gazi University0 个研究点目标入组 87 人开始时间: 2024年7月22日最近更新: 2024年8月19日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方: Gazi University
入组人数: 87

研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

Mean salivary IL-1beta, TNF-alpha levels were elevated , and mean NO level was decreased in BD patients with gingivitis compared to patients without BD. In contrast, mean NO level in crevicular fluid was higher in Behcet's patients with periodontitis than in patients without BD. Furthermore, among Behcet's patients, those with vascular involvement had lower salivary NO level compared to patients without vascular involvement

研究设计

研究类型: Observational

入排标准

年龄范围: 26 Years 至 51 Years（—）
性别: All

入选标准

•Periodontitis was diagnosed with a severity of Stage II, pocket depth 3 mm and Stage III, pocket depth 5 mm, a generalized pattern according to the criteria by the criteria 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. Gingivitis was diagnosed as according to a BOP score 10%, without attachment loss and radiographic bone loss.Patients were diagnosed according to the International Criteria for Behcet Disease (ICBD). ICBD is based on ocular lesions, genital ulcers, oral aphthous ulcers, skin manifestations, vascular involvement and positive pathergy test. Systemic involvement associated with BD, current symptoms and the use of any systemic medications were recorded.

排除标准

•Stage IV periodontitis
•autoimmune diseases

研究者

发起方

Gazi University

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