Vascular Affection in Behcet Disease
Not yet recruiting
- Conditions
- Behcet Disease and Vascular Involvement
- Registration Number
- NCT06280430
- Lead Sponsor
- Assiut University
- Brief Summary
To measure the level of serum elafin in patients with behcet disease and to assess the correlation between serum elafin and vascular affection and their relation with disease activity
- Detailed Description
Behcet disease is a chronic multi systemic inflammatory disease characterized by recurrent oral and genital ulcers and multiple systemic affection . Elafin is a serine protease inhibitor produced mainly by epithelial cells . previous studies documented the role of serum elafin in pathogenesis of behcet disease.vascular complications may be one if the earliest manifestation leading to the diagnosis of behcet disease.
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
- patients diagnosed as behcet disease Age (20-45)
Exclusion Criteria
- age <20 and >45 Other autoimmune diseases Risk factors (ischemic heart disease, diabetes) Chronic conditions (malignancy, chronic kidney disease)
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To measure the level of serum elafin in behcet patients and compare it with control group Within 1year Measure the level of serum elafin in behcet and its relation to disease activity and vascular involvement
- Secondary Outcome Measures
Name Time Method