Evaluating the Effect of Oxygentherapy on Concentration at Chronic Lung Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 32
- 试验地点
- 2
- 主要终点
- Response time
研究概览
简要总结
The objective is to study the cognitive functions in patients with chronic obstructive lung disease (COLD) and patients with interstitial lung disease (ILD) compared to healthy controls. The cognitive functions are tested with and without oxygen therapy to clarify the effect of oxygen therapy. Driving simulations is used to test the cognitive functions.
The hypothesis is that patients with chronic lung disease have decreased cognitive functions and that oxygen therapy will increase their cognitive functions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •COLD with forced expiratory volume at one second (FEV1) <50%, without long term oxygen therapy
- •COLD with FEV1 <50%, with long term oxygen therapy
- •ILD with diffusion capacity of lung for carbon monoxide (DLCO) < 50%, without long term oxygen therapy
排除标准
- •comorbidity which decreases cognitive function
- •comorbidity which decreases concentration
- •physical comorbidity which makes it impossible to complete the test
结局指标
主要结局
Response time
时间窗: During the 45 min. of driving in the simulator
Measuring the mean amount of response time from the number "2" appears on the screen until the patient reacts
Standard deviation from the centre of the road
时间窗: During the 45 min. of driving in the simulator
Measuring how far from the centre of the road the patient has been driving in the driving simulation
Number of nil responses
时间窗: During the 45 min. of driving in the simulator
Measuring the number of times the patients doesn't react to the number "2" on the screen
Number of off-road events per hour
时间窗: During the 45 min. of driving in the simulator
The number of times the car is off-road during the driving simulation
次要结局
未报告次要终点