Comparision between two uterotonics : Carbetocin versus Oxytoci
- Conditions
- Health Condition 1: O722- Delayed and secondary postpartum hemorrhage
- Registration Number
- CTRI/2023/09/057571
- Lead Sponsor
- Datta Meghe Institute of Higher Education and Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Consenting, healthy pregnant women, with singleton pregnancy, undergoing elective caesarean section at term with regional anesthesia.
Women with placenta previa, placental abruption, and multiple gestation as these conditions are associated with an increased risk of PPH. Women with pregnancy-related complications and disorders such as pre-eclampsia, gestational diabetes, or pre-existing diseases such as insulin-dependent diabetes, cardiovascular or renal diseases, or hypo-/hyperthyroidism (these conditions could possibly interfere with hemodynamic parameters). Women taking medication with a known impact on the cardiovascular system. Women undergoing caesarean section with general anesthesia were also excluded, as carbetocin is licensed for use only with regional anesthesia.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Effects of both drugs on maternal heart rate (HR) and blood pressure (BP).Timepoint: 1 hour (starting from drug administration till one hour thereon).
- Secondary Outcome Measures
Name Time Method The impact of both drugs on post operative blood loss, and need of additional uterotonics, and changes in post operative hemoglobin and uterine tone.Timepoint: Post operative 1 hour