Automated Chest Compression in Cardiac Arrest

Completed

• Conditions: Cardiac Arrest

• Registration Number: NCT00641069
• Lead Sponsor: Beaujon Hospital

Brief Summary

To evaluate the effect of use of automated chest compression device on blood pressure in patients presenting with cardiac arrest. Higher systolic, diastolic and mean blood pressures are expected.

Detailed Description

The protocol compares arterial pressures produced by an automated self-adjusting load-distributing band device (AutoPulse™ 100, Zoll®) with those of manual cardiopulmonary resuscitation in refractory out-of-hospital cardiac arrest. Each patient will receive first manual compressions and then automated resuscitation.

Patients presenting with cardiac arrest are treated following standard advanced life support guidelines. They are intubated and ventilated, received epinephrine and defibrillation if appropriate. Manuel chest compressions are continued. An arterial catheter is placed to monitor hemodynamics continuously as we usually do in this case. Patients are included at this stage. Three blood pressure values (every 1 minutes) are recorded. Then, the automated band device is started up without any pause, following our procedure for refractory cardiac arrest. Three blood pressure values are recorded again, during automated cardiopulmonary resuscitation.

Study Timeline

• Study Start: 2008-02
• Study First Submitted: 2008-03-18
• Study First Submitted QC: 2008-03-18
• Study First Posted: 2008-03-21
• Primary Completion: 2009-01
• Study Completion: 2009-01
• Status Verified: 2009-07
• Last Update Submitted: 2009-07-14
• Last Update Posted: 2009-07-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Age ≥ 18
• Refractory cardiac arrest

Exclusion Criteria

• Defective invasive arterial blood pressure monitoring

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Diastolic blood pressures produced by manual and then by automated chest compressions will be recorded for each patient	Instantaneously

Secondary Outcome Measures

Name	Time	Method
Systolic blood pressures produced by manual and then by automated chest compressions will be recorded for each patient	Instantaneously
Mean blood pressures produced by manual and then by automated chest compressions will be recorded for each patient	Instantaneously

Trial Locations

Locations (1)

Departement of Anesthesiology, Intensive Care and EMS, Beaujon University Hospital; 🇫🇷 Clichy, France