The Effect of Chlorella on Glycemic Control of Diabetes

Not Applicable

• Conditions: Diabetes
• Interventions: Drug: Chlorella

• Registration Number: NCT01301287
• Lead Sponsor: Cardinal Tien Hospital

Brief Summary

Chlorella, a type of unicellular fresh water algae, has been a popular foodstuff in Asia, especially in Taiwan. Recent studies have shown the hypoglycemic effects of Chlorella through increasing glucose uptake in the liver and muscle, lowering serum free fatty acid levels, or activation of PPAR gamma receptor. However, the hypoglycemic effect in diabetic patients have not been studied. In order to clarify the hypoglycemic effects and mechanism of Chlorella in diabetic patients, the investigators conducted a 12-week randomized, double-blind, placebo-control trial on diabetic patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-01
• Status Verified: 2011-02
• Study First Submitted: 2011-02-22
• Study First Submitted QC: 2011-02-22
• Last Update Submitted: 2011-02-22
• Study First Posted: 2011-02-23
• Last Update Posted: 2011-02-23

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• 18-70 years old
• type 2 diabetes with less than 2 kinds of oral antidiabetes drugs
• Hba1c: 7.0-9.0

Exclusion Criteria

• type 1 diabetes
• pregnancy
• acute infectious disease
• autoimmune disease
• hemodynamic unstable

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Chlorella	Chlorella	-

Primary Outcome Measures

Name	Time	Method
HbA1c	12 weeks

Secondary Outcome Measures

Name	Time	Method
Insulin concentration during oral glucose tolerance test	12 weeks	All subjects received the first oral glucose tolerance test before intervention(week 0), and the second oral glucose tolerance test on week 12.

Trial Locations

Locations (1)

Cardinal Tien Hospital; 🇨🇳 New Taipei City, Taiwan