Dexamethasone for ESPB in Pain Management After Pediatric Idiopathic
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- First need of opioid analgesia
研究概览
简要总结
Effect of perineurial dexamethasone on erector spinal plane block duration for pediatric, idiopathic scoliosis surgery.
详细描述
This study proposes to explore the effect of perineurial Dexamethasone on erector spinal plane block duration for pediatric idiopathic scoliosis surgery.
Children need good analgesia after scoliosis surgery. Peripheral nerve blocks have provided a safe, effective method to control early postoperative pain when symptoms are most severe.
The safety of local anesthesia is essential in children due to the much lower toxicity threshold of local anesthetics. An effective adjuvant, such as Dexamethasone, could allow for a higher dilution of local anesthetics while maintaining and enhancing their analgesic effect.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 10 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •children scheduled for idiopathic scoliosis surgery
- •age >10 and <18 years
排除标准
- •age < 10 years
- •age < 18 years
- •infection at the site of the regional blockade
- •coagulation disorders
- •immunodeficiency
- •ASA= or >4
- •steroid medication in regular use
研究组 & 干预措施
DEXAMETHASONE
0.2% ropivacaine + 0.1mg/kg Dexamethasone for erector spinae plane block
干预措施: Dexamethasone (Drug)
CONTROL
0.2% ropivacaine for erector spinae plane block
干预措施: 0.9%NaCl (Drug)
结局指标
主要结局
First need of opioid analgesia
时间窗: 48 hours after surgery
Time after surgery when the patient needs opiate for the first time
次要结局
- Opioid consumption(48 hours after procedure)
- Numerical Rating Scale [range 0:10](48 hours after surgery)
- MEP(durring surgery)
- Nerve damage [range 0-4](48 hours after surgery)
- glucose(48 hours after surgery)