Role of Cyclooxygenase-2 expression as a prediction of persistent cervical low grade squamous intraepithelial lesio

Phase 1

Recruiting

• Conditions: 1. Women age 21- 65 year with histological diagnosis of CIN 1 who attending colposcopic clinic at chulalongkorn hospital2. PAP and cervical tissue biopsy were examined and determined by pathologists; Cervical intraepithelial neoplasia , COX- 2 expression, CIN 1

• Registration Number: TCTR20191030003
• Lead Sponsor: Faculty of Medicine, Research affairs Chulalongkorn University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-10-30
• Study Completion: 2020-03-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 175

Inclusion Criteria

Women age 21-65 year with histological diagnosis of CIN 1 who attending colposcopic clinic at chulalongkorn hospital

PAP and cervical tissue biopsy were examined and determined by pathologists in chulalongkorn hospital

Exclusion Criteria

History of cervical cancer
Previous hysterectomy
Previous radiation
Prior CIN 1 diagnosis or treatment with laser ablation or cryotherapy within 12 month
Incomplete data record

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Score of COX-2 expression after pathologic report improved Allred score

Secondary Outcome Measures

Name	Time	Method
age, parity, partner, first SI, previous treatment, previous PAP result, education, income, after pathologic report improved Interview and record form