Microneedling Versus Carboxytherapy Either With or Without Platelet Rich Plasma in Treating Stria Distensae Rubra
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Reduction in the size of the stria distensae rubra
研究概览
简要总结
The aim of this study is to evaluate and compare the efficacy and safety of microneedling and carboxytherapy either with or without platelet-rich plasma in the treatment of striae distensae rubra.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Female patients.
- •Age ranging from 18-45 years old.
- •Fitzpatrick skin type III-IV.
- •Striae distensae rubra on the abdomen (bilateral and more or less symmetrical).
排除标准
- •Patients taking immunosuppressants or having any disease affecting wound healing including diabetes.
- •Patients receiving systemic glucocorticoids for chronic health conditions.
- •Patients with chronic dermatologic diseases such as psoriasis and vitiligo.
- •Pregnant and lactating females.
- •Patients with a tendency for keloid formation.
- •Patients with endocrine disturbance.
- •Patients with autoimmune diseases, systemic diseases such as severe anemia, respiratory, cardiac, renal or liver disorder.
- •Patients with bleeding and coagulation disorders.
- •Patients who received any form of treatment for their SD in the past 6 months.
研究组 & 干预措施
treated with microneedling
microneedling with topical application of PRP on one side of abdomen and microneedling only on the other side
干预措施: microneedling (Device)
treated with carboxytherapy
carboxytherapy with intradermal injection of PRP on one side of abdomen and carboxytherapy only on the other side
干预措施: Carboxytherapy (Device)
结局指标
主要结局
Reduction in the size of the stria distensae rubra
时间窗: group I: six sessions over 18 weeks , group II: 6 sessions over 12 weeks, followed in both groups by three months of follow up
will be assessed by digital photography, actual measurement of the stria before and after treatment, and objective assessment of the percent of improvement
次要结局
未报告次要终点