Anaesthesia Cognitive Evaluation (ACE) Study

Not Applicable

Completed

• Conditions: Patients with osteoarthritis which is medically managed and those requiring total hip replacement surgery.; Musculoskeletal - Osteoarthritis

• Registration Number: ACTRN12607000049471
• Lead Sponsor: A/Prof Brendan Silbert

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-01-16
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 400

Inclusion Criteria

Scheduled for elective hip replacement surgery for osteoarthritis or control patients with medically managed osteoarthritis who: do not have neurological deficit; give informed consent; have no contraindication to neuropsychological testing. The patients must reside in accessible proximity to the hospital to enable investigators to administer baseline neuropsychological testing at home.

Exclusion Criteria

1.Pre-existing neurological or clinically evident neurovascular disease (e.g. TIA, stroke);2.Score of less than 26 on the Mini Mental State Examination or CDR>1 (i.e. exclude dementia);3.Anticipated difficulty with neuropsychological assessment, such as English not being the prime language, blindness, deafness;4.Associated medical problems that may lead to significant complications and subsequent loss to follow-up (ASA Physical Status IV or higher);Geographical remoteness that may make it difficult to test patients at home.

Study & Design

• Study Type: Observational
• Study Design: Not specified