Enhanced Genetic Awareness and Genetic Evaluation for Men Through Technology, ENGAGEMENT Study

Active, not recruiting

• Conditions: Prostate Carcinoma
• Interventions: Other: Educational Intervention; Other: Survey Administration; Other: Interview

• Registration Number: NCT04789018
• Lead Sponsor: Thomas Jefferson University

Brief Summary

This study assesses perceived usefulness of a web-based virtual prostate cancer genetics board for providers across academic, community, and veteran affairs settings to discuss prostate cancer genetics cases, precision treatment, and screening recommendation. Information gained from interviews and surveys of participants taking part in the virtual genetics board may lend insights into perceived usefulness, perceived ease of use, acceptability, self-efficacy, genetics knowledge, and barriers/facilitators to implementation to refine the process.

Detailed Description

PRIMARY OBJECTIVE:

I. To assess perceived usefulness of a virtual genetics board.

SECONDARY OBJECTIVE:

I. To assess acceptability/feasibility, perceived ease of use, self-efficacy for recommendations, genetics knowledge.

OUTLINE:

Participants complete a survey about genetic knowledge and self efficacy and then attend virtual genetics board. After virtual genetics board meeting, participants complete a second survey about perceived usefulness, ease of use, acceptability, feasibility, self-efficacy and genetic knowledge. Participants may also complete a semi-structured interview after virtual genetics board.

Study Timeline

• Study Start: 2020-01-21
• Study First Submitted: 2021-02-19
• Study First Submitted QC: 2021-03-04
• Study First Posted: 2021-03-09
• Status Verified: 2025-01
• Last Update Submitted: 2025-01-02
• Last Update Posted: 2025-01-03
• Primary Completion: 2025-06-24
• Study Completion: 2025-06-24

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 118

Inclusion Criteria

• Non-genetic providers who perform PCA genetic testing for men in their practices (medical oncologists, radiation oncologists, urologists, primary care providers, mid-level providers)

Exclusion Criteria

• Non-medical providers

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Observational (survey, virtual genetic board, interview)	Educational Intervention	Participants complete a survey about genetic knowledge and self efficacy and then attend virtual genetics board. After virtual genetics board meeting, participants complete a second survey about perceived usefulness, ease of use, acceptability, feasibility, self-efficacy and genetic knowledge. Participants may also complete a semi-structured interview after virtual genetics board.
Observational (survey, virtual genetic board, interview)	Survey Administration	Participants complete a survey about genetic knowledge and self efficacy and then attend virtual genetics board. After virtual genetics board meeting, participants complete a second survey about perceived usefulness, ease of use, acceptability, feasibility, self-efficacy and genetic knowledge. Participants may also complete a semi-structured interview after virtual genetics board.
Observational (survey, virtual genetic board, interview)	Interview	Participants complete a survey about genetic knowledge and self efficacy and then attend virtual genetics board. After virtual genetics board meeting, participants complete a second survey about perceived usefulness, ease of use, acceptability, feasibility, self-efficacy and genetic knowledge. Participants may also complete a semi-structured interview after virtual genetics board.

Primary Outcome Measures

Name	Time	Method
Mean Likert scaled perceived usefulness scores of the virtual genetics board	After virtual genetics board	Perceived usefulness will be judged against a benchmark mean score of 5/7.

Secondary Outcome Measures

Name	Time	Method
Perceived ease of use	After virtual genetics board	Will be summarized by means, standard deviations, and 95% confidence intervals.
Means or changes in means of Likert scaled acceptability/feasibility	Before and after virtual genetics board	Will be summarized by means, standard deviations, and 95% confidence intervals.
Self-efficacy for recommendations	Before and after virtual genetics board	Will be summarized by means, standard deviations, and 95% confidence intervals.
Change in mean scores on 17 genetics knowledge test questions	Baseline up to post-virtual genetics board	Will be summarized by means, standard deviations, and 95% confidence intervals.

Trial Locations

Locations (1)

Sidney Kimmel Cancer Center at Thomas Jefferson University; 🇺🇸 Philadelphia, Pennsylvania, United States