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Clinical Trials/NCT02832908
NCT02832908
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Evaluation of the Physiopathological Phenomena and the Haemodynamic and Cerebral Metabolic Effects From Semi-seated Position to Lying Position in Patients With Brain Trauma

University Hospital, Montpellier1 site in 1 country90 target enrollmentDecember 2014

Overview

Phase
N/A
Intervention
Not specified
Conditions
Traumatic Brain Injury
Sponsor
University Hospital, Montpellier
Enrollment
90
Locations
1
Primary Endpoint
ASSESSMENT OF THE CEREBRAL OXYGENATION
Last Updated
9 years ago

Overview

Brief Summary

Brain trauma is an important burden in traumatologic intensive care. In these patients the treatment is guided by a cluster of multimodal monitoring parameters. Despite this it is difficult to assess the actual physiopathologic status of the brain. Changing the position of these patients (semi-seated to lying position) causes changes in the hémodynamics brain conditions, so in monitoring parameters . The analysis of these changes can givr us valuable clinically informations.

Detailed Description

Severe brain trauma (CGS \< 8 ) are included. PIC, PA, PVC, EKG, airway pressure, SjO2 and NIRSS are continuously monitored. The patients are in semi seated (30°) position. Once a day they are in supine (0°) for 30 minutes. We record every parameters before and at the end of this supine period. After time domain and frequency domain signal processing, this parameters are compared to deduct clinical relevant conclusions.

Registry
clinicaltrials.gov
Start Date
December 2014
End Date
December 2016
Last Updated
9 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • patients with a severe head trauma estimated by the Glasgow Coma Scale and by the Glasgow Outcome Scale
  • age \> 18

Exclusion Criteria

  • Other neurological pathology

Outcomes

Primary Outcomes

ASSESSMENT OF THE CEREBRAL OXYGENATION

Time Frame: UP TO 6 MONTHS

Study Sites (1)

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