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Evaluation of the Physiopathological Phenomena and the Haemodynamic and Cerebral Metabolic Effects From Semi-seated Position to Lying Position in Patients With Brain Trauma

Not Applicable
Conditions
Traumatic Brain Injury
Registration Number
NCT02832908
Lead Sponsor
University Hospital, Montpellier
Brief Summary

Brain trauma is an important burden in traumatologic intensive care. In these patients the treatment is guided by a cluster of multimodal monitoring parameters. Despite this it is difficult to assess the actual physiopathologic status of the brain. Changing the position of these patients (semi-seated to lying position) causes changes in the hémodynamics brain conditions, so in monitoring parameters . The analysis of these changes can givr us valuable clinically informations.

Detailed Description

Severe brain trauma (CGS \< 8 ) are included. PIC, PA, PVC, EKG, airway pressure, SjO2 and NIRSS are continuously monitored.

The patients are in semi seated (30°) position. Once a day they are in supine (0°) for 30 minutes. We record every parameters before and at the end of this supine period.

After time domain and frequency domain signal processing, this parameters are compared to deduct clinical relevant conclusions.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
90
Inclusion Criteria
  • patients with a severe head trauma estimated by the Glasgow Coma Scale and by the Glasgow Outcome Scale
  • age > 18
Exclusion Criteria
  • Other neurological pathology

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
ASSESSMENT OF THE CEREBRAL OXYGENATIONUP TO 6 MONTHS
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Hôpital Lapeyronie - Département Anesthésie Réanimation A

🇫🇷

Montpellier, France

Hôpital Lapeyronie - Département Anesthésie Réanimation A
🇫🇷Montpellier, France
Jean Paul ROUSTAN, MD
Contact
04 67 33 82 56
jp-roustan@chu-montpellier.fr
Jean Paul ROUSTAN, MD, phone 0467338256
Principal Investigator

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