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Recruiting
- Conditions
- von Willebrand diseasehemophilia carrierpost partum hemorrhage (PPH)
- Registration Number
- NL-OMON23871
- Lead Sponsor
- niversity Medical Center Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 135
Inclusion Criteria
Ongoing pregnancy beyond 10 weeks after the last menstruation
-Carrier of hemophilia A or B or Von Willebrand disease type 1, type 2 or type 3
Exclusion Criteria
-Another concomitant coagulation disorder that needs a deviation of the treatment advises according to the revised national guideline on the management of pregnancy in hemophilia carriers and von Willebrand disease
-Use of therapeutic or intermediate dose LMWH before delivery
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The incidence of severe PPH, defined as 1000mL or more blood loss within the first 24 hours after delivery
- Secondary Outcome Measures
Name Time Method The incidence of primary PPH, defined as 500mL or more blood loss within the first 24 hours after delivery<br /><br>The incidence of late PPH, defined as excessive vaginal blood loss between 24 hours and 12 weeks after delivery needing hospital admission<br /><br>Results of the PRO questionnaires <br>