A comparative clinical study of Durva Malahara and Gandhakadya Malahara in the management of Eczema
试验速览
- 阶段
- 2/3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Changes in itching, discolouration, crusting, dryness, scaling, burning sensation
研究概览
简要总结
Eczema is a chronic, relapsing, and itchy inflammatory skin condition characterized by erythema, oedema, vesicles, weeping and skin thickening. 30 patients of eczema fulfilling inclusion criteria were selected from OPD and 15 patients each were allocated into group A and group B on the basis of block randomization. Durva malahara and Gandhakadya Malahara were administered to group A and group B respectively for externally for 6 weeks and the assessemnet was made through changes in signs-symptoms and EASI score of eczema. Both groups showed significant improvement in sign-symptoms and EASI score of eczema. Group A showed better improvement in erythema and oedema while group B showed slightly better improvement in excoriation and lichenification however the difference in signs of EASI score was not strong enough to confirm the real difference between the treatments of both group which showed statistically not significant result.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 16.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients between age group of 16-60 years.
- •Patients having minimum 3-4 signs and symptoms of eczema fulfilling the diagnosis.
排除标准
- •Patients having any other diseases like AIDS, STD, TB, DM and other disorders which lead to fatal condition for the patients.
- •Pregnant and lactating women.
- •Patients who are on corticosteroid drugs or immune-suppressants and past history of steroidal use in the last 6 months.
- •Other concomitant skin disease occurring with allergic reaction of any other disease.
结局指标
主要结局
Changes in itching, discolouration, crusting, dryness, scaling, burning sensation
时间窗: Before and after the intervention of trial drug
次要结局
- Changes in EASI score(Before and after the intervention of trial drug)
研究者
Dr Bansi B Monpara
Maganbhai Adenwala Mahagujarat University